Gloves: chemical resistance and comparision charts

Glove Selection Guide

Links to chemical compatibility and permeation charts are show at the bottom of this page
if you wish more information.

Use this checklist to choose the appropriate type of protective glove for your job. The Glove Selection Chart also provides advantages and disadvantages for specific glove types.

What to do
How to do it
1. Identify the hazards of the material(s) you’ll be working with. 1. Base selection of glove type and material on the type of exposure and nature of the hazard. Some chemicals can easily penetrate gloves that work very well for other chemicals.
Consider these factors:

  • Chemical type
  • Temperature extremes, cryogenic properties
  • Physical hazards (sharps, piercing objects)
  • pH
  • Toxicity
  • Infectious potential of biological hazards


2. Determine if you’ll have incidental or extended contact with the hazardous materials. 1. Incidental contact (little or no direct contact with the hazardous material) includes these situations:

  • Accidental spills or splashes
  • Accidental overspray from a dispensing device
  • Handling infectious agents that require barrier protection
  • To prevent contamination of materials during handling

If you will have incidental contact, go to the Step 3.

2. Extended contact includes these situations:

  • Handling highly contaminated materials
  • Submerging hands in a chemical or other hazardous substance
  • Need for physical protection from temperature extremes or sharp/piercing objects

If you will have extended contact, go to Step 4.

3. For incidental contact, follow these selection guidelines. 1. Type of glove: Disposable, surgical-type gloves are appropriate for incidental contact.
2. Nitrile gloves are preferred over latex because of their chemical resistance, their tendency to visibly rip when punctured, and to prevent possible latex allergies.

  • See the Glove Selection Chart below for advantages and disadvantages of commonly used surgical-type gloves.

3. Disposable glove usage:

  • Check for rips or punctures before use.
  • Remove and replace gloves immediately with new ones when a chemical spills or splashes on them.
  • Never wash or reuse disposable gloves.
  • Always remove glove before touching common objects such as doorknobs, phones, or elevator buttons.
4. For extended contact, follow these guidelines. 1. Type of glove: More substantial gloves are required for extended use.

  • Norfoil gloves are recommended for highly toxic materials and materials that are absorbed through the skin.
  • See the Glove Selection Chart below for advantages and disadvantages of commonly used gloves for extended contact.

2. Reusable glove usage: Many gloves intended for extended contact are reusable.

  • Check the gloves for:
    • Rips or punctures before and after each use
    • Prior contamination
    • Signs of degradation (change in color or texture)
    • Replace gloves as soon as signs of degradation appear.
    • Wash after removal and air dry in the laboratory.
    • Consider wearing inner surgical gloves for extra protection.


Glove Comparison Chart

Summary: Consult this chart for an overview of commonly used glove types for laboratory use and their general advantages and disadvantages.

Note: These photos are examples. Glove colors and appearances will vary. Many other models are commercially available in each glove category.

Glove material

Intended use

Advantages and disadvantages

Example Photos

Nitrile Incidental contact (disposable exam glove)Extended contact (thicker reusable glove)
  • Excellent general use glove. Good for solvents, oils, greases, and some acids and bases.
  • Clear indication of tears and breaks.Good alternative for those with latex allergies.
Butyl rubber Extended contact
  • Good for ketones and esters.
    Poor for gasoline and aliphatic, aromatic, and halogenated hydrocarbons.
Neoprene Extended contact
  • Good for acids, bases, alcohols, fuels, peroxides, hydrocarbons, and phenols.
  • Poor for halogenated and aromatic hydrocarbons.
  • Good for most hazardous chemicals.
Norfoil Extended contact
  • Good for most hazardous chemicals.
  • Poor fit (Note: Dexterity can be partially regained by using a heavier weight Nitrile glove over the Norfoil/Silver Shield glove.
Viton Extended contact
  • Good for chlorinated and aromatic solvents.
  • Good resistance to cuts and abrasions.
  • Poor for ketones.
  • Expensive.
Polyvinyl chloride (PVC) Specific use
  • Good for acids, bases, oils, fats, peroxides, and amines.
  • Good resistance to abrasions.
  • Poor for most organic solvents.
Polyvinyl alcohol (PVA) Specific use
  • Good for aromatic and chlorinated solvents.
  • Poor for water-based solutions.
Cryogenic Resistant MaterialLeather Specific use For use with cryogenic materials.Designed to prevent frostbite. Note: Never dip gloves directly into liquid nitrogen.

Chemical compatibility and permeation charts for from vendors